Neomycin Sulfate CAS#1405-10-3

Neomycin Sulfate CAS#1405-10-3

Neomycin Sulfate CAS#1405-10-3

Broad-Spectrum Antibacterial Activity: Effective against both gram-positive and gram-negative bacteria, making it versatile for treating bacterial infections.


Multiple Mechanisms of Action: Inhibits bacterial protein synthesis by binding to prokaryotic ribosomes and also modulates cellular enzymes such as PLC, PLD, and PLA2.


Protects DNA Integrity: Inhibits DNase I–induced DNA degradation, supporting cellular protection in research and medical applications.


Topical Therapeutic Use: Commonly used to prevent or treat bacterial skin infections, offering a reliable option for dermatological applications.

Quality Assurance

Rigorous quality control and full regulatory compliance assured.

Sustainable Development

Sustainable processes cut waste, lower emissions, and save costs.

Specialty Solutions

Tailored fine chemicals that enhance efficiency and outcomes.

Chemical Manufacturer

A trusted manufacturer capable of stable, high-volume production and supply.

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Product Description

Product Description-Neomycin Sulfate CAS#1405-10-3


Neomycin sulfate is an aminoglycoside antibiotic and calcium channel inhibitor. It targets prokaryotic ribosomes to block protein synthesis, active against Gram-positive and Gram-negative bacteria. It also modulates PLC, PLD, PLA2 and calcium signaling, and inhibits DNase I-mediated DNA breakdown. Mainly for bacterial skin infections; ineffective against fungi and viruses.

Product Applications-Neomycin Sulfate CAS#1405-10-3


Used for the prevention and treatment of conditions such as dysentery, diarrhea, and stunted growth in livestock and poultry—including pigs, chickens, and cattle—caused by Escherichia coli or Salmonella infections. It can also be used to treat enteritis in fish and shrimp in aquaculture.

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Product Data

Chemical Properties-Neomycin Sulfate CAS#1405-10-3



Melting point

>187°C (dec.)

Alpha

D20 +54° (c = 2 in H2O)

Bulk density

640kg/m3

Refractive index

56 ° (C=10, H2O)

Fp

56℃

Storage temp

2-8°C

Solubility

H2O: 50 mg/mL As a stock solution. Stock solutions should be filter sterilized and stored at 2-8°C. Stable at 37°C for 5 days.

Form

powder

Color

white to slightly yellow

PH

5.0-7.5 (50g/l, H2O, 20℃)

Biological source

Streptomyces sp

Water Solubility

Soluble in water

Merck

14,6454

Stability

Stable. Incompatible with strong oxidizing agents.

InChIKey

OIXVKQDWLFHVGR-VTSVPHRWSA-N

LogP

-3.655 (est)

CAS DataBase Reference

1405-10-3(CAS DataBase Reference)

EPA Substance Registry System

Neomycin sulfate (1405-10-3)



Safety Information-Neomycin Sulfate CAS#1405-10-3



Hazard Codes

Xn,Xi

Risk Statements

42/43-22

Safety Statements

23-36/37-45-22-36-24/25

WGK Germany

3

RTECS

QP4375000

F

8

TSCA

Yes

HS Code

29419000

Toxicity

LD50 oral in mouse: > 8gm


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