Broad Anti-Tumor Activity: It is effective against multiple cancers, including leukemia, lymphoma, lung cancer, breast cancer, cervical cancer, and osteosarcoma.
Wide Clinical Application Scope: It is used in the treatment of various malignant diseases such as squamous cell carcinoma, choriocarcinoma, and hydatidiform mole.
Rapid Elimination from the Body: Approximately 90% of the drug is excreted in urine within 12 hours after oral administration, indicating fast metabolic clearance.
Defined Pharmacological Profile: It has a known active metabolite (7-hydroxymethotrexate) and documented toxicity data (rat intravenous LD50: 14 mg/kg), supporting its studied pharmacokinetic characteristics.
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Product Description-Methotrexate CAS#59-05-2
Methotrexate is an effective antitumor agent for acute lymphoblastic leukemia, lymphoma, malignant hydatidiform mole, choriocarcinoma, squamous cell carcinoma, lung, cervical, breast cancer and osteosarcoma. After oral dosing, around 90% of the parent drug is excreted in urine within 12 hours; its primary metabolite is 7-hydroxymethotrexate. The intravenous LD₅0 in rats is 14 mg/kg.
Product Applications-Methotrexate CAS#59-05-2
This agent is an effective anti-tumor drug, used in the treatment of conditions such as acute lymphoblastic leukemia, lymphoma, malignant hydatidiform mole, choriocarcinoma, squamous cell carcinoma, lung cancer, cervical cancer, breast cancer, and osteosarcoma. Following oral administration, 90% of the parent drug is excreted in the urine within 12 hours; its primary metabolite is 7-hydroxymethotrexate.
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Chemical Properties-Methotrexate CAS#59-05-2
Safety Information-Methotrexate CAS#59-05-2
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