Natamycin CAS#7681-93-8

Natamycin CAS#7681-93-8

Natamycin CAS#7681-93-8

Broad-Spectrum Antifungal Activity: Pimaricin is highly effective against a wide variety of fungi, including Candida, Aspergillus, Fusarium, Penicillium, and others, making it versatile for medical and food applications.


Safe Natural Preservative: Widely used in the food industry, it acts as a natural preservative that prevents fungal contamination, extending product shelf life without compromising safety.


Targeted Mechanism of Action: By binding to ergosterol in fungal cell membranes, it disrupts membrane function and nutrient transport, effectively suppressing fungal growth with precision.


Proven Medical Effectiveness: Pimaricin is clinically used to treat fungal keratitis and other infections, offering reliable therapeutic benefits with a well-established safety profile.

Quality Assurance

Rigorous quality control and full regulatory compliance assured.

Sustainable Development

Sustainable processes cut waste, lower emissions, and save costs.

Specialty Solutions

Tailored fine chemicals that enhance efficiency and outcomes.

Chemical Manufacturer

A trusted manufacturer capable of stable, high-volume production and supply.

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Product Description

Product Description-Natamycin CAS#7681-93-8


Pimaricin (natamycin, INN), a natural macrolide polyene antifungal from Streptomyces natalensis fermentation, treats fungal keratitis and works against fungi including Candida, Aspergillus, Fusarium and Penicillium. It is also widely used as a natural food preservative. It binds to fungal membrane ergosterol, disrupting membrane fusion to inhibit fungal growth, and blocks amino acid and glucose transport via membrane protein interference.

Product Applications-Natamycin CAS#7681-93-8


Pimaricin serves as a surface preservative coating for Italian cheeses to suppress molds and yeasts. Tasteless, odorless and colorless, it does not penetrate cheese. It strongly inhibits nearly all molds and yeasts without harming bacteria, preserving natural cheese ripening and flavor. It can be applied by dipping, spraying or mixing into cheese coatings, with typical dosages of 300–2,000 ppm.

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Product Data

Chemical Properties-Natamycin CAS#7681-93-8



Product Name:

Natamycin

Synonyms:

NataMycin, A 5283, Delvolan, Delvocid, Myprozine, Natacyn, Natafucin, PiMafucin, PiMafugin, A5263, CL 12625, E235;Natamycin(FermentionProcess);(1R*,3S*,5R*,7R*,8E,12R*,14E,16E,18E,20E,22R*,24S*,25R*,26S*)]-22-[(3-Amino-3,6-dideoxy-β-D-mannopyranosyl)oxy]-1,3,26-trihydroxy-12-methyl-10-oxo-6,11,28-trioxatricyclo[22.3.1.05,7]octacosa-8,14,16,18,20-pentaene-25- carboxylic acid;NATAMYCIN;PIMAFUCIN;PIMARICIN;PIMARICIN, STREPTOMYCES CHATTANOOGENSIS;antibiotica-5283

CAS:

7681-93-8

MF:

C33H47NO13

MW:

665.73

EINECS:

231-683-5

Product Categories:

Food additives;Food & Feed ADDITIVES;Antifungal (Topical);Intermediates & Fine Chemicals;Pharmaceuticals;ERGOSTAT;antibiotic;raw materials;Food additive;7681-93-8

Mol File:

7681-93-8.mol

Melting point

2000C (dec)

Alpha

D20 +278° (c = 1 in CH3COOH)

Boiling point

952℃

Density

1.0 g/mL at 20 °C(lit.)

Bulk density

200kg/m3

Refractive index

1.5960 (estimate)

Fp

>110°(230°F)

Storage temp

Keep in dark place,Inert atmosphere,2-8°C

Solubility

Soluble in DMSO

Form

Aqueous suspension

Pka

PKa 4.6(50% aq. MeOEtOH) (Uncertain);8.35 (Uncertain)

Color

Cream colored

Water Solubility

0.41g/L(21 ºC)

Sensitive

Light Sensitive

Merck

13,6453

BRN

1614878

Stability

Light sensitive

InChIKey

NCXMLFZGDNKEPB-FFPOYIOWSA-N

LogP

0.880 (est)

EPA Substance Registry System

6,11,28-Trioxatricyclo[22.3.1.05,7]octacosa-8,14,16,18,20-pentaene-25-carboxylic acid, 22-[(3-amino-3,6-dideoxy-.beta.-D-mannopyranosyl)oxy]-1,3,26-trihydroxy-12-methyl-10-oxo-, (1R,3S,5R,7R,8E,12R,14E,16E,18E,20E,22R,24S,25R,26S)- (7681-93-8)


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