D-a-Tocopherol succinate CAS#4345-03-3

Powerful Antioxidant: Acts as a potent antioxidant, protecting cells from oxidative stress.

Radioprotective Effect: Protects against gamma-radiation by inducing granulocyte-colony stimulating factor.

Anticancer Activity: Induces apoptosis in human gastric cancer and neuroblastoma cells, and inhibits mesothelioma cell proliferation.

Regulates Cell Growth: Down-regulates fibroblast growth factor receptor-1 (FGFR-1) to inhibit tumor cell proliferation.

admin@lhychemical.com

+86 193 5386 9308

Contact us



Quality Assurance

Rigorous quality control and full regulatory compliance assured.



Sustainable Development

Sustainable processes cut waste, lower emissions, and save costs.



Specialty Solutions

Tailored fine chemicals that enhance efficiency and outcomes.



Chemical Manufacturer

A trusted manufacturer capable of stable, high-volume production and supply.

ABOUT THE PRODUCT

Product Description

Product Description-D-a-Tocopherol succinate CAS#4345-03-3

Tocopherol succinate (CAS 4345-03-3) is a potent antioxidant. It shields mice from gamma radiation via granulocyte-colony stimulating factor induction. It triggers apoptosis in gastric cancer and neuroblastoma cells, and suppresses mesothelioma cell proliferation by downregulating FGFR-1.

Product Applications-D-a-Tocopherol succinate CAS#4345-03-3

This novel, highly selective antineoplastic agent synergizes with TRAIL (Apo2 ligand). It suppresses mesothelioma proliferation by selectively downregulating fibroblast growth factor receptors and boosts the antitumor efficacy of dendritic cell vaccines.

ABOUT THE PRODUCT

Factory Environment

ABOUT THE PRODUCT

Product Data

Chemical Properties-D-a-Tocopherol succinate CAS#4345-03-3

Melting point	~76 °C(lit.)
Boiling point	625.8±55.0 °C(Predicted)
density	1.002±0.06 g/cm3(Predicted)
vapor pressure	0Pa at 20℃
storage temp.	-20°C
solubility	Practically insoluble in water, very soluble in methylene chloride, soluble in acetone and in anhydrous ethanol.
form	Solid
pka	4.35±0.17(Predicted)
color	White or off-white
Odor	Little or no odor
biological source	synthetic
λmax	286nm(EtOH)(lit.)
Merck	14,9495
BRN	4038233
Specific Activity	1210IU/g
Stability:	Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.
Cosmetics Ingredients Functions	ANTIOXIDANT
InChIKey	IELOKBJPULMYRW-NJQVLOCASA-N
SMILES	CC(C)CCC[C@@H](C)CCC[C@@H](C)CCC[C@]1(C)CCc2c(C)c(OC(=O)CCC(O)=O)c(C)c(C)c2O1
LogP	12 at 25℃
CAS DataBase Reference	4345-03-3(CAS DataBase Reference)
EPA Substance Registry System	D-.alpha.-Tocopheryl acid succinate (4345-03-3)

Safety Information-D-a-Tocopherol succinate CAS#4345-03-3

WGK Germany	1
RTECS	EJ9984000
F	8-10-23
TSCA	TSCA listed
HS Code	2936280000
Storage Class	11 - Combustible Solids
Toxicity	LD50 oral in rat: > 7gm/kg

ABOUT US

Shipped From the Factory

ABOUT THE PRODUCT

ABOUT US