Exceptional Catalytic Activity: Exhibits acylation and esterification activity approximately 10⁴–10⁶ times higher than pyridine.
Strong Nucleophilic Catalyst: The electron-donating dimethylamino group greatly enhances nucleophilic substitution efficiency.
Effective for Low-Reactivity Substrates: Efficiently catalyzes acylation of alcohols and amines with high steric hindrance or low reactivity.
Versatile in Organic Synthesis: Widely used in acyl transfer reactions, including asymmetric synthesis with chiral DMAP catalysts.
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Product Description
Product Description-4-Dimethylaminopyridine CAS#1122-58-3
4-Dimethylaminopyridine (DMAP) is a powerful nucleophilic acylation catalyst. Its dimethylamino group activates the pyridine nitrogen, accelerating acylation and esterification of alcohols, amines and acids, even sterically hindered or low-reactivity substrates. Its catalytic activity is 10⁴–10⁶ times higher than pyridine. Chiral DMAP is widely used for asymmetric acyl transfer reactions.
Product Applications-4-Dimethylaminopyridine CAS#1122-58-3
It is used for water softening, high-purity water production, radioactive element refining, iodine extraction from seaweed, antibiotic purification and industrial wastewater treatment.
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Chemical Properties-4-Dimethylaminopyridine CAS#1122-58-3
Safety Information-4-Dimethylaminopyridine CAS#1122-58-3
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